Methods and formulations for treating vascular disease
AssigneeEndoperfusion Solutions, LLC
InventorsJaipal SINGH, Yan XIN, Osama ABOUL-MAGD
Life of this patent
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Abstract
Devices and methods for treating a vascular disease in a subject are disclosed that involve acute administration of a statin locally to a diseased segment of a blood vessel in the subject.
Claims29
A method for treating a vascular disease in a subject in need thereof, comprising acutely administering a statin locally to a diseased segment of a blood vessel in the subject.
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A kit comprising a drug-eluting balloon catheter and a pharmaceutical composition comprising a therapeutically effective amount of the statin to treat a vascular disease in a subject in need thereof when administered locally to a diseased segment of a blood vessel in the subject via the drug-eluting balloon catheter.
25-32. (canceled)
A catheter balloon completely or partially coated with a statin, wherein a therapeutically effective amount of the statin is released and/or bioavailable of when the balloon is inflated intraluminally.
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A pharmaceutical formulation comprising a statin encapsulated in a lipid-based particles, wherein the statin is present in therapeutically effective amount to treat a vascular disease in a subject in need thereof when administered locally to a diseased segment of a blood vessel in the subject.
42-45. (canceled)
Dependencies are inferred from the claim text.