Tunable device for treating eye disease

2:

• The device according to claim 1, wherein the fluid channels form a hexagonal pattern with each channel having a height and first width to produce a desired fluid flow rate.

3:

• The device according to claim 1, wherein a first portion of the plate has a first thickness and a second portion of the plate has a second thickness.

4:

• The device according to claim 3, wherein the first thickness is greater than the second thickness.

5:

• The device according to claim 3, wherein the first portion includes an extension portion and the second portion includes a main body portion.

6:

• The device according to claim 1, wherein the interconnected fluid channels have dimensions between 10×14 and 12×18 micrometers (“μm”) and the plate includes a neck width between 2 and 5 millimeters (“mm”).

7:

• The device according to claim 1, wherein the plate is formed from a ceramic material selected from the group consisting of alumina, silicon nitride, silica, hafnium oxide, titanium nitride, and titanium carbide.

8:

• The device according to claim 1, wherein the first coating has a thickness of about 0.1 μm to about 10 μm.

9:

• The device according to claim 1, wherein the first coating is a parylene polymer including at least one of parylene C, parylene D, parylene N, a derivative thereof, or a combination thereof.

10:

• The device according to claim 1, wherein the second coating is aluminum oxide or a parylene polymer.

11:

• The device according to claim 1, wherein at least one of the first coating or the second coating includes at least one of a biocompatible film, a porous coating, or a lubricious coating.

12:

• The device according to claim 11, wherein the biocompatible film includes polytetrafluoroethylene (PTFE) or enhanced PTFE.

13:

• The device of claim 1, wherein the series of fluid channels includes a plurality of open-ended channels that are interconnected to form an intersecting grid pattern of fluid pathways.

14:

• The device of claim 1, wherein the plate has a core thickness between 300 and 800 nanometers.

15:

• The device of claim 1, wherein the plate structure includes at least one notch along a perimeter, the notch being indicative as to whether the first surface or the second surface is visible to a surgeon.

16:

• The device of claim 1, wherein the plate structure includes at least one geometric feature for attachment to patient tissue.

18:

• The method according to claim 17, wherein the treatment application includes at least one of:
• lowering intraocular pressure, glaucoma, hydrocephalus, plastic surgery drainage of hematoma, seroma, or serous fluids, cell growth, a delivery of cells, a delivery of nucleic acids, a delivery of nanoparticles, or a conduit for a delivery of drugs.

19:

• The method of claim 17, wherein the dimensions of the device include at least one of a thickness of the device, dimensions of the device, a thickness of the coating, dimensions of fluid microchannels channels, or dimensions of open cells.

20:

• The method of claim 17, wherein the mechanical properties include at least one of a desired bending stiffness, a tensile elasticity, or a fluid flow rate.

21:

• The method of claim 17, wherein a first portion of the device is formed to have a first thickness and a second portion of the device is formed to have a second thickness.

22:

• The method according to claim 21, wherein the first thickness is greater than the second thickness.

23:

• The method of claim 17, wherein the dimensions are additionally determined based on patient placement information.

24:

• The method of claim 17, wherein the layer of aluminum oxide is deposited at a specified thickness based on the determined dimensions.