Mixed functionalized graphene structure and corresponding field-effect transistor biosensor

Abstract

The present invention relates a mixed functionalized graphene structure comprising a graphene surface; 1-pyrenebutanoic acid succinimidyl ester (PBASE) molecules; molecules of at least one type of polycyclic aromatic hydrocarbon (PAH) compounds; and biomolecules; wherein both the molecules of PBASE and the molecules of at least one type of PAH compounds are non-covalently linked to the graphene surface, wherein the biomolecules are linked to the PBASE molecules, and wherein the mixed functionalized graphene structure has a surface roughness (Rms) between around 0.01±1.00 μm and around 0.25±1.00 μm respect to the surface roughness (Rms) of non-functionalized graphene, wherein Rms is measured by atomic force microscopy (AFM). The present invention relates also to a method for preparing said mixed functionalized graphene structure, to a functionalized graphene structure obtainable by said method. Finally, the present invention relates to a Field-Effect Transistor (FET) chip comprising said mixed functionalized graphene structure, to an electronic device for biological sample analysis comprising said chip, to a method for electronic biological sample analysis by using said device and to the use of the mixed functionalized graphene structure in FET biosensors.

Dependencies are inferred from the claim text.