Antibody and use thereof for the treatment of cancer

A monoclonal antibody that specifically binds to an epitope comprising the amino acid sequence SEQ ID NO:

• 2 (GSETWKTIITKN), SEQ ID NO:
• 3 (IGSETWKTIITKNLHYKD), SEQ ID NO:
• 4 (GSETWKTIITKNC) or SEQ ID NO:
• 5 (GGGSETWKTIITKN) and capable of inhibiting the IL-13/IL13Rα2-mediated signaling or an antigen-binding fragment of said antibody, wherein the monoclonal antibody is selected from the group consisting of
• a) an antibody comprising
• the three heavy-chain CDRs of sequences SEQ ID NO:
• 6, SEQ ID NO:
• 7 and SEQ ID NO:
• 8 and
• the three light-chain CDRs of sequences SEQ ID NO:
• 9, SEQ ID NO:
• 10 and SEQ ID NO:
• 11;
• and
• b) an antibody comprising
• the three heavy-chain CDRs of sequences SEQ ID NO:
• 12, SEQ ID NO:
• 13 and SEQ ID NO:
• 14, and
• the three light-chain CDRs of sequences SEQ ID NO:
• 15, SEQ ID NO:
• 16 and SEQ ID NO:
• 17.