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US 2024/0181064 A1Published application
Ganciclovir compositions and related methods
AssigneeExela Pharma Sciences, LLC
InventorsSreerama Murthy Mallipeddi, Jonathan E. Sterling, Phanesh B. Koneru
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Abstract
Gancyclovir formulations that are ready-to-use, substantially particulate free, and stable upon storage are disclosed. Methods of manufacture and administration of such compositions are also provided.
Claims18
A stable, injectable, ready to administer, sterile, particulate-matter-free, aqueous parenteral dosage form for parenteral administration to a subject, consisting essentially of:
- ganciclovir at a concentration of from 1 mg/ml to 3 mg/ml;
- a tonicity agent;
- and
- optionally a pH adjuster,
- wherein the composition has a pH of from 5 to 9.
2 more elements
A container comprising a stable, ready to administer, sterile ganciclovir injectable composition consisting essentially of:
- ganciclovir at a concentration of 1 mg/ml to 3 mg/ml;
- a tonicity agent;
- and
- optionally a pH adjuster
- wherein the composition has pH of from 5 to 9 and the composition has an osmotic pressure of 250-350 mOsmol/Kg.
2 more elements
Dependencies are inferred from the claim text.