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US 2024/0181044 A1Published application
Glycan modified spike receptor binding domain nanoparticles and method of use thereof as a coronavirus disease 2019 (covid-19) vaccine
OwnerDaniel Kulp, Yuanhan Wu +4inventors
InventorsDaniel Kulp, Yuanhan Wu, Kylie M. Konrath, Kevin Liaw, Ziyang Xu, David Weiner
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Abstract
Disclosed herein are glycan-coated RBD immunogens, engineered nanoparticle vaccines comprising glycan-coated RBD immunogens and methods of use thereof for SARS-COV-2 vaccines.
Claims21
A nucleic acid molecule encoding a glycan-coated immunogen modified to encode at least one non-native site for glycan modification.
-16. (canceled)
Dependencies are inferred from the claim text.