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AssigneesAugusta University Research Institute, Inc., University of Miami, The United States Government AS Represented By the Dept. of Veterans Affairs
InventorsNeal L. WEINTRAUB, Maritza J. ROMERO LUCAS, Rudolf LUCAS, Andrew SCHALLY, Renzhi CAI
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Provided herein are compositions and methods of use thereof for the treatment of metabolic disease such as diabetes and obesity. One embodiment provides a method of treating a metabolic disease or syndrome in a subject in need thereof by administering to the subject a therapeutically effective amount of a growth hormone releasing hormone (GHRH) antagonist or a pharmaceutical composition comprising the GHRH antagonist to reduce triglyceride-rich-lipoproteins (TRL) in the subject to treat the metabolic condition or syndrome.
A method of treating a metabolic disease or syndrome in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a growth hormone releasing hormone (GHRH) antagonist or a pharmaceutical composition comprising the GHRH antagonist to reduce triglyceride-rich-lipoproteins (TRL) in the subject to treat the metabolic condition or syndrome.
A method of treating an obesity in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a growth hormone releasing hormone (GHRH) antagonist.
A method for reducing or inhibiting reduce triglyceride-rich-lipoproteins (TRL) levels in a subject in need thereof comprising administering to the subject an effective amount of a GHRH antagonist or a pharmaceutical composition containing the GHRH antagonist to reduce TRL levels in the subject.
Dependencies are inferred from the claim text.