Mri display output reflecting contrast agent concentration as a function of time
AssigneeHologic, Inc.
InventorsJiachao Liang, Jimmy R. Roehrig
Life of this patent
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Abstract
A magnetic resonant imaging (MRI) review workstation includes a control processor, and a display integrated or otherwise operatively coupled with the control processor, wherein the control processor is configured to receive and analyze magnetic resonant imaging information pertaining to an imaged volume of tissue, and to cause to be displayed on the display output information that reflects or is otherwise indicative of an absorption rate of a contrast agent in the volume of tissue.
Claims20
1-20. (canceled)
An image review workstation comprising:
- a display;
- at least one controller operatively coupled to the display;
- and
- a memory coupled to the at least one controller, the memory storing instructions that, when executed by the at least one controller, performs a set of operations comprising:
- receiving respective electronic magnetic resonant imaging (MRI) data of an imaged tissue volume acquired by different MRI scanners over respective periods of time after a respective contrast agent is introduced into a patient while at least a portion of the patient is positioned within respective different MRI scanners;
- converting a plurality of signal enhancement ratio curves associated with the respective electronic MRI data from the different MRI scanners into an absorption rate curve, the absorption rate curve describing absorption rates of the respective contrast agent in the imaged tissue volume and compensating for a non-linear relationship between an MRI signal generated by the different MRI scanners during imaging of the imaged tissue volume and a concentration of the respective contrast agent over time;
- wherein the absorption rate curve is determined by deriving a signal intensity ratio for the imaged tissue volume based on an actual absorption rate of the respective contrast agent in the imaged tissue volume for all of the different MRI scanners;
- normalizing the derived signal intensity ratio for the imaged tissue volume so that a signal enhancement ratio is independent of the different MRI scanners used to generate the electronic MRI data;
- and
- displaying, on the display, the absorption rate curve of the respective contrast agent in the imaged tissue volume.
A magnetic resonant imaging (MRI) image review workstation comprising:
- a display;
- at least one controller operatively coupled to the display;
- and
- a memory coupled to the at least one controller, the memory storing instructions that, when executed by the at least one controller, performs a set of operations comprising:
- receiving electronic MRI data of an imaged tissue volume acquired by a plurality of MRI scanners over a period of time after a contrast agent is introduced into a patient;
- converting a plurality of signal enhancement ratio curves associated with the electronic MRI data from the plurality of MRI scanners into an absorption rate curve, the absorption rate curve describing absorption rates of the contrast agent in the imaged tissue volume and compensating for a non-linear relationship between an MRI signal during imaging of the imaged tissue volume and a concentration of the contrast agent over time, wherein the absorption rate curve is determined by deriving a signal intensity ratio for the imaged tissue volume based on an actual absorption rate of the contrast agent in the imaged tissue volume for each of the plurality of MRI scanners;
- normalizing the derived signal intensity ratio for the imaged tissue volume so that a signal enhancement ratio is independent of the plurality of MRI scanners used to generate the electronic MRI data;
- and
- displaying, on the display, the absorption rate curve of the contrast agent in the imaged tissue volume.
Dependencies are inferred from the claim text.