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US 2024/0175846 A1Published application
Differential Mobility Spectrometer/Mass Spectrometer Interface With Greater Than 10 L/Min Transport Gas Flow
AssigneeDH Technologies Development Pte. Ltd.
InventorsThomas COVEY, Yang KANG, Bradley B. SCHNEIDER
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Abstract
Methods and systems for performing differential mobility spectrometry are provided herein. Systems and methods in accordance with various aspects of the present teachings provide differential mobility separation at drift gas volumetric flow rates greater than about 10 L/min, which are substantially higher than those previously reported and conventionally used in DMS-based analyses.
Claims25
A method of analyzing ions in a differential mobility spectrometer, comprising:
- introducing a drift gas at a flow rate greater than about 10 L/min through an inlet of a differential mobility spectrometer;
- performing differential mobility separation on ions within the drift gas using the differential mobility spectrometer as the drift gas transports the ions therethrough.
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A system comprising:
- a housing having an inlet and an outlet;
- at least two parallel plate electrodes disposed within said housing and separated from one another by a fixed distance, the volume between the two electrodes defining an analytical gap through which ions are transported from the inlet toward the outlet;
- a voltage source for providing RF and DC voltages to at least one of the parallel plate electrodes to generate an electric field, the electric field for passing through selected ions species based on mobility characteristics;
- and
- a drift gas supply for supplying a gas that flows through the inlet at a flow rate greater than about 10 L/min.
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Dependencies are inferred from the claim text.