US 2024/0174622 A1 · COMPOUND AND RADIOACTIVE LABELING COMPOUND

Abstract

The compound of the present invention includes a structure having: a chelating part capable of coordinating with a radioactive metal ion; a first atomic group containing an albumin-binding part; and a second atomic group containing a PSMA molecule-binding part, wherein the first atomic group and the second atomic group are bonded with each other through the chelating part, or the chelating part is bonded from between the first atomic group and the second atomic group so that it makes a branch. The present invention also provides: a radiolabeled compound in which the compound is coordinated with a radioactive metal ion; and a method for manufacturing a radiolabeled compound.

Claims14

Dependent claims

A compound comprising a structure having:

a chelating part capable of coordinating with a radioactive metal ion;
a first atomic group including an albumin-binding part;
and
a second atomic group including a PSMA molecule-binding part,
wherein the first atomic group and the second atomic group are bonded with each other through the chelating part.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application

18/548,716Filed 2 Mar 2022

Priority

JP 2021-0340264 Mar 2021

Published

30 May 2024

Term ends

Not estimatedThe source records don’t support an estimate.

Classification13 codes

C07D 257/02
Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms: not condensed with other rings
A61K 31/395
Heterocyclic compounds: having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
A61K 51/04
Characterised by the carrier , i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus: organic compounds
A61K 51/0402
Organic compounds: carboxylic acid carriers, fatty acids

Compound and radioactive labeling compound

Life of this patent

Compound and radioactive labeling compound

Life of this patent

Abstract

Claims14