Microwave treatment of tissue

A method of treating or preventing a disease or condition caused by and/or associated with:

• aberrant expression of the IL8 gene
• aberrant expression of the SOCS3 gene
• aberrant expression of the EGR1 gene
• aberrant expression of the CD79A gene
• aberrant expression of the IL1B gene
• aberrant expression of the TNFRSF13C gene;
• said method comprising administering a subject in need of treatment, microwave energy.

A method of upregulating the expression of one or more of the following gene(s):

• the KIT gene;
• and/or
• the BAD gene;
• and/or
• the ID4 gene;
• and/or
• the RUNX1T1 gene;
• and/or
• the AKT3 gene;
• said method comprising exposing the relevant gene to microwave energy.

A method or in vitro method of down-regulating the expression of one or more of the following gene(s):

• the IL8 gene;
• and/or
• the SOCS 3 gene;
• and/or
• the EGR1 gene;
• and/or
• the CD79A gene;
• and/or
• the IL1B gene;
• and/or
• the TNFRSF13C gene;
• and/or
• the GADD45B gene;
• and/or
• the Notch3 gene;
• and/or
• the CCND2 gene;
• and/or
• the WNT5A gene;
• said method comprising exposing the relevant gene to microwave energy.

A method or in vitro method of treating or preventing a disease or condition caused by and/or associated with:

• downregulated expression of the KIT gene;
• and/or
• downregulated expression of the BAD gene;
• and/or
• downregulated expression of the ID4 gene;
• and/or
• downregulated expression of the RUNX1T1 gene;
• and/or
• downregulated expression of the AKT3 gene;
• said method comprising administering a subject suffering from or predisposed/susceptible to any such disease, microwave energy.

A method of treating or preventing a disease or condition caused by and/or associated with:

• upregulated expression of the IL8 gene;
• and/or
• upregulated expression of the SOCS3 gene;
• and/or
• upregulated expression of the EGR1 gene;
• and/or
• upregulated expression of the CD79A gene;
• and/or
• upregulated expression of the IL1B gene;
• and/or
• upregulated expression of the TNFRSF13C gene;
• and/or
• upregulated expression of the GADD45B gene;
• and/or
• upregulated expression of the Notch3 gene;
• and/or
• upregulated expression of the CCND2 gene;
• and/or
• upregulated expression of the WNT5A gene;
• said method comprising administering a subject suffering from or predisposed/susceptible to any such disease, microwave energy.

A method of modulating:

• the PI3K pathway;
• and/or
• the RAS pathway;
• and/or
• the MAPK pathway;
• and/or
• the Notch pathway;
• and/or
• the Wnt pathway;
• and/or
• the Transcriptional Regulation (KEGG) pathway;
• and/or
• the JAK/STAT pathway;
• and/or
• the TGF-B pathway;
• and/or
• the Hedgehog pathway;
• said method comprising exposing the pathway to microwave energy at a dose sufficient to modulate the expression of the relevant pathway.

A method of treating or preventing a disease or condition caused by and/or associated with:

• aberrant expression of the PI3K pathway;
• and/or
• aberrant expression of the RAS pathway;
• and/or
• aberrant expression of the MAPK pathway;
• and/or
• aberrant expression of the Notch pathway;
• and/or
• aberrant expression of the Wnt pathway;
• and/or
• aberrant expression of the Transcriptional Regulation (KEGG) pathway;
• and/or
• aberrant expression of the JAK/STAT pathway;
• and/or
• aberrant expression of the TGF-B pathway;
• and/or
• aberrant expression of the Hedgehog pathway;
• and/or
• said method comprising administering a subject in need of treatment, microwave energy at a dose sufficient to modulate the expression of the relevant pathway.

Use of microwave energy to upregulate the expression of one or more of the following gene(s):

• the KIT gene;
• and/or
• the BAD gene;
• and/or
• the ID4 gene;
• and/or
• the RUNX1T1 gene;
• and/or
• the AKT3 gene.

Use of microwave energy to down-regulate the expression of one or more of the following gene(s):

• the IL8 gene;
• and/or
• the SOCS 3 gene;
• and/or
• the EGR1 gene;
• and/or
• the CD79A gene;
• and/or
• the IL1B gene;
• and/or
• the TNFRSF13C gene;
• and/or
• the GADD45B gene;
• and/or
• the Notch3 gene;
• and/or
• the CCND2 gene;
• and/or
• the WNT5A gene;
• said method comprising exposing the relevant gene to microwave energy.