US 2024/0173481 A1Published application

Syringe with tandem dual chambers

AssigneeBecton, Dickinson and Company

InventorsAkshay Srikanth, Vignesh Murugesan, Nachiket Karmarkar, Achutha Prasad, Preran Rao

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Abstract

A dual chamber syringe facilitates selective drug mixing, dosing, and administration through catheters or other vascular accessing devices (VADs), as well as pre- or post-administration flushing of catheters with a single syringe instrument. A syringe barrel incorporates an outlet, such as a Luer connector, variable-volume, axially tandem primary and secondary fluid chambers, with nested respective plungers, plunger rods capable of selective translation within the barrel interior along a common axis, and plunger stoppers. The secondary fluid chamber is incorporated within the primary plunger. A selectively resealable valve disposed within the barrel interior, selectively isolates the secondary fluid chamber from fluid communication with the primary fluid chamber and/or the outlet of the syringe barrel. In some embodiments, the valve is a duckbill-type valve or an umbrella valve. In some embodiments, the syringe is prepackaged with flushing solution in the secondary fluid chamber.

Claims19

Dependent claims

A syringe comprising:

a substantially cylindrically shaped barrel, which defines an inner side wall, the barrel having an open proximal end, and a distal end, the distal end of the barrel including a connector defining an outlet lumen therethrough, the outlet lumen in fluid communication with an interior of the barrel, the interior defined by the open proximal end, the distal end, and the inner side wall;
nested primary and secondary plungers, disposed within the barrel interior, respectively having primary and secondary plunger rods capable of selective translation within the barrel interior along a common axis;
a primary stopper coupled to a distal end of the primary plunger, the primary stopper having a proximal end surface facing the proximal end of the barrel and a distal end surface facing the distal end of the barrel, the primary stopper defining a through aperture between its proximal and distal end surfaces, in fluid communication with the outlet lumen;
a secondary stopper coupled to a distal end of the secondary plunger, the secondary stopper having a distal end surface facing the distal end of the barrel;
a resealable valve disposed within the barrel interior, axially offset, along the common axis, toward the distal end of the barrel away from the distal end surface of the secondary stopper, the resealable valve having an inlet in fluid communication with the distal end surface of the secondary stopper and an outlet in fluid communication with the through aperture of the primary stopper and the outlet lumen;
a primary fluid chamber within the barrel interior, defined between the distal end surface of the primary stopper and the distal end of the barrel, volume of the primary fluid chamber being selectively variable by translation of the primary plunger rod;
a secondary fluid chamber, within the barrel interior, defined between the distal end surface of the secondary stopper and the valve inlet, in fluid communication with the valve inlet, volume of the secondary fluid chamber being selectively variable by translation of the secondary plunger rod;
wherein, when the valve is closed the secondary fluid chamber is isolated from the outlet lumen, so that translation of the primary plunger rod only aspirates fluid into or dispenses fluid out of the primary chamber, via the outlet lumen;
and
wherein, when the valve is open the secondary fluid chamber is fluid communication with the outlet lumen, so that translation of the secondary plunger rod dispenses fluid out of the secondary chamber, via the outlet lumen.

7 more elements

A syringe comprising:

a substantially cylindrically shaped barrel, which defines an inner side wall, the barrel having an open proximal end, and a distal end, the distal end of the barrel including a connector defining an outlet lumen therethrough, the outlet lumen in fluid communication with an interior of the barrel, the interior defined by the open proximal end, the distal end, and the inner side wall;
a primary plunger having tubular construction, defining an interior surface and a through-bore aperture on the distal end thereof;
a secondary plunger nested and captured within the interior surface of the tubular primary plunger, the secondary plunger establishing fluid communication with the through-bore aperture of the primary plunger, and the outlet lumen;
nested primary and secondary plunger rods, capable of selective translation within the barrel interior along a common axis, respectively coupled to the primary plunger and the secondary plunger;
a primary stopper, having a cup-shaped profile, defining a radially projecting skirt in abutting contact with the inner side wall of the barrel, the primary stopper coupled to a distal end of the primary plunger, the primary stopper having a proximal end surface facing the proximal end of the barrel and a distal end surface facing the distal end of the barrel, the primary stopper defining a through aperture between its proximal and distal end surfaces, in fluid communication with through-bore aperture of the primary plunger and the outlet lumen;
a secondary stopper coupled to a distal end of the secondary plunger, the secondary stopper having a distal end surface facing the distal end of the barrel;
a resealable one-way valve disposed within the barrel interior, axially offset, along the common axis, toward the distal end of the barrel away from the distal end surface of the secondary stopper, the resealable valve having an inlet in fluid communication with the distal end surface of the secondary stopper and an outlet in fluid communication with the through aperture of the primary stopper, the through-bore aperture of the primary plunger, and the outlet lumen;
a primary fluid chamber within the barrel interior, defined between the distal end surface of the primary stopper and the distal end of the barrel, volume of the primary fluid chamber being selectively variable by translation of the primary plunger rod;
a secondary fluid chamber, within the interior of the primary plunger, between the distal end surface of the secondary stopper and the valve inlet, in fluid communication with the valve inlet, volume of the secondary fluid chamber being selectively variable by translation of the secondary plunger rod;
wherein, when the valve is closed the secondary fluid chamber is isolated from the outlet lumen, so that translation of the primary plunger rod only aspirates fluid into or dispenses fluid out of the primary chamber, via the outlet lumen;
and
wherein, when the valve is open the secondary fluid chamber is fluid communication with the outlet lumen, so that translation of the secondary plunger rod dispenses fluid out of the secondary chamber, via the outlet lumen.

9 more elements

A syringe comprising:

a substantially cylindrically shaped barrel, which defines an inner side wall, the barrel having an open proximal end, and a distal end, the distal end of the barrel including a connector defining an outlet lumen therethrough, the outlet lumen in fluid communication with an interior of the barrel, the interior defined by the open proximal end, the distal end, and the inner side wall;
a primary plunger having tubular construction, defining an interior surface and a through-bore aperture on the distal end thereof;
a secondary plunger nested and captured within the interior surface of the tubular primary plunger, the secondary plunger establishing fluid communication with the through-bore aperture of the primary plunger, and the outlet lumen;
nested primary and secondary plunger rods, capable of selective translation within the barrel interior along a common axis, respectively coupled to the primary plunger and the secondary plunger;
a primary stopper, having a proximal end surface facing the proximal end of the barrel and a distal end surface facing the distal end of the barrel, the primary stopper defining a through aperture between its proximal and distal end surfaces, which is in fluid communication with the through-bore aperture of the primary plunger and the outlet lumen;
a secondary stopper coupled to a distal end of the secondary plunger, the secondary stopper having a distal end surface facing the distal end of the barrel, the secondary plunger and secondary stopper captured within the interior surface of the tubular primary plunger;
an umbrella valve coupled to the respective distal ends of the tubular primary plunger, and the primary stopper, the umbrella valve defining a radially projecting skirt oriented in opposing relationship with the distal end surface of the primary stopper, and the umbrella valve having a proximal end surface facing the proximal end of the barrel and a distal end surface facing the distal end of the barrel;
a primary fluid chamber within the barrel interior, defined between the respective distal end surfaces of the primary stopper and the umbrella valve and the distal end of the barrel, volume of the primary fluid chamber being selectively variable by translation of the primary plunger rod;
a secondary fluid chamber, within the interior of the primary plunger, between the distal end surface of the secondary stopper and the proximal end surface of the umbrella valve, in fluid communication with the through aperture of the primary stopper and the through-bore aperture of the primary plunger, volume of the secondary fluid chamber being selectively variable by translation of the secondary plunger rod;
wherein, when the umbrella valve is closed, the secondary fluid chamber is isolated from the outlet lumen, so that translation of the primary plunger rod only aspirates fluid into or dispenses fluid out of the primary chamber, via the outlet lumen;
and
wherein, when the umbrella valve is open, the secondary fluid chamber is fluid communication with the outlet lumen, so that translation of the secondary plunger rod dispenses fluid out of the secondary chamber, via the outlet lumen.

9 more elements

Dependencies are inferred from the claim text.

Facts

Application: 18/071,897Filed 30 Nov 2022
Published: 30 May 2024
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

A61M 5/19
Syringes: having more than one chamber
A61M 5/31511
Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing…:…
A61M 5/3134
Syringe barrels: characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
A61M 5/31596
Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing…:…

Family

No related US applications are recorded in the indexed filing history.

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