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US 2024/0173435 A1Published application
Gene delivery for prevention and treatment of baldness
AssigneeNew Jersey Institute of Technology
InventorsXiaoyang Xu, Zhongyu Li, William Ho
Life of this patent
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Abstract
Ionizable cationic lipid compounds have an amine moiety from amino alcohols and a lipid moiety from a lipid synthesized via esterification. The ionizable cationic lipid compounds which comprise an amino alcohol mediated ionizable cationic lipid compound are useful for in vivo or in vitro delivery of one or more nucleic acid agents including DNA, siRNA, a microRNA, an mRNA, a RNAi, and a plasmid.
Claims20
A nucleic acid construct comprising a domain hybridizing with early coding regions of the androgen receptor gene.
Dependencies are inferred from the claim text.