Probe for Hydrogen Sulfide Detection, Method for Manufacturing Same, and Composition for Hydrogen Sulfide Detection, Comprising Same

A method for manufacturing a probe for hydrogen sulfide detection, the method comprising the steps of:

• preparing a first intermediate (5-(4-(diethylamino)phenyl)-N-methylthiophen-3-amine) (5a);
• obtaining a second intermediate (2-(4-(diethylamino)phenyl)-7-(4-methoxyphenyl)-4-methyl-6,7-dihydrothieno[3,2-b]pyridin-5(4H)-one) (6a) by quenching the first intermediate(5a) with water and extraction;
• obtaining a third intermediate (6-bromo-2-(4-(diethylamino)phenyl)-7-(4-methoxyphenyl)-4-methylthieno[3,2-b]pyridin-5(4H)-one) (7a) by quenching the second intermediate (6a) with water and extraction;
• obtaining a fourth intermediate (2-(4-(Diethylamino)phenyl)-7-(4-methoxyphenyl)-4-methylthieno[3,2-b]pyridin-5(4H)-one) (8a) by quenching the third intermediate (7a) with water and extraction;
• obtaining KF (2-(4-(diethylamino)phenyl)-7-(4-hydroxyphenyl)-4-methylthieno[3,2-b]pyridin-5(4H)-one) by quenching the fourth intermediate(8a) with water and extraction;
• and
• obtaining KF-DNBS (4-(2-(4-(diethylamino)phenyl)-4-methyl-5-oxo-4,5-dihydrothieno[3,2-b]pyridin-7-yl)phenyl 2,4-dinitrobenzenesulfonate) by quenching the KF with water and extraction.