Therapeutic composition based on dhodh-inhibiting neurolaena leaves for the treatment of rna virus infections

A method for preparing a dry extract of a diluted mother tincture of dried leaves of Neurolaena lobata, the method comprising the following steps:

• i) preparing a mixture of dried leaves of Neurolaena lobata in sugar cane alcohol at 50°, said mixture having a mass concentration of between 15 and 20 g/L;
• ii) macerating said mixture under agitation for about 21 days;
• iii) filtering, after the step of macerating, the mixture on “cartridges” of porosity 50-75 μm and a liquid filtrate is obtained, corresponding to a mother tincture of dried leaves of Neurolaena lobata, and a solid retentate;
• iv) diluting said liquid mother tincture to ¼ by adding an aqueous solution, and an aqueous-alcoholic solution is thus obtained;
• v) evaporating the alcohol contained in this solution by a rotary evaporator, until an aqueous solution is obtained;
• and
• vi) consolidating and freeze-drying the aqueous solution thus obtained to obtain a dry extract of the diluted mother tincture of dried leaves of Neurolaena lobata.