Tumor-targeting salmonella gallinarum strain and use thereof
AssigneesIndustry Foundation of Chonnam National University, Choybiolab Co., Ltd.
InventorsHyon El CHOY, Jae Ho JEONG, Dae Jin LIM, Hyung Ju LIM, Kwangsoo KIM
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Abstract
The present invention relates to a tumor-targeting Salmonella gallinarum strain and the use thereof. The tumor-targeting Salmonella gallinarum strain has excellent tumor proliferation inhibitory activity and enables tumor-specific targeting, and thus can be utilized for treatment and imaging of tumors without any side effects.
Claims19
An attenuated Salmonella gallinarum strain, lacking guanosine tetraphosphate (ppGpp) production capability.
A method for providing information about tumor analysis, the method comprising the steps of:
- administering the Salmonella gallinarum strain to a subject;
- detecting bioluminescence of the strain;
- and
- determining the presence of tumor in the subject if the bioluminescence is detected.
Dependencies are inferred from the claim text.