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US 2024/0092836 A1Published application
Cyclic peptide having ctla-4 inhibitory activity and use thereof
AssigneeGeneFrontier Corporation
InventorsKanehisa KOJOH, Kumiko TSUIHIJI, Shizue KATOH, Mikiko NAKAMURA
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Abstract
The present invention provides a cyclic peptide which comprises the amino acid sequence represented by formula (I) X1-His-Pro-X4-Leu-X6-X7-X8-Ser-X10-His-Phe (I) in the cycle and has an activity to specifically bind to human CTLA-4, wherein X1, X4, X6, X7, X8 and X10 are each independently any amino acid.
Claims19
A cyclic peptide which comprises the amino acid sequence represented by formula (I):
- X1-His-Pro-X4-Leu-X6-X7-X8-Ser-X10-His-Phe (I)
- in the cycle and has an activity to specifically bind to human CTLA-4, wherein X1, X4, X6, X7, X8 and X10 are each independently any amino acid.
-20. (canceled)
-23. (canceled)
Dependencies are inferred from the claim text.