Ivermectin formulation in oral solution

Abstract

The present invention relates to a formulation of Ivermectin in oral solution which allows proper absorption, enabling the drug to be consumed at any time. In particular, the oral lipid composition is designed with the appropriate selection of a medium-chain triglyceride oil, a hydrophilic cosolvent and an antioxidant, so as to influence the absorption/digestibility of the poorly water-soluble active ingredient and facilitate bioavailability and bioactivity for the administration of the oral solution in drops. The formulation includes Ivermectin in a lipid medium including a cosolvent and an antioxidant in combination with an oily solvent to form an oral solution for administration in drops. The field of the invention is related to improving the bioavailability of insoluble drugs such as Ivermectin for administration in oral drop forms based mainly on lipids without compromising stability or creating impurities.

Dependencies are inferred from the claim text.