Compositions including filamentous fungal biomass and cultured animal cells, and methods of forming and using
AssigneeThe Regents of the University of California
InventorsDavid BLOCK, Minami OGAWA
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Abstract
Set forth herein is a composition that includes a fungal pellet and animal cells, wherein the animal cells are in connection with the fungal pellet. The animal cells can be located on the exterior surface of the fungal pellet, the interior of the fungal pellet, or both. The fungal pellet can include intact fungal cells. The fungal pellet can be substantially inviable. In an example, the pellet can be heat-treated, chemically treated, or lyophilized. The animal cells can be mammalian cells, wherein the mammalian cells may be non-human mammalian cells.
Claims31
A composition comprising a fungal pellet and animal cells, wherein the animal cells are in connection with the fungal pellet, wherein the fungal pellet is inviable.
A process for producing a composition of animal cells, comprising:
- a. obtaining a fungal pellet comprising a fungus, wherein the fungus is inviable or inactivated;
- b. seeding a plurality of animal cells, which are viable, onto the fungal pellet to produce a seeded fungal pellet;
- and
- c. incubating the seeded fungal pellet under conditions wherein the animal cells remain viable.
Dependencies are inferred from the claim text.