Back to results
US 2024/0059646 A1Published application
Resorcinol-based compounds and uses thereof
AssigneesSutter Bay Hospitals, Organix, Inc.
InventorsSean D. McAllister, Pierre-Yves Desprez, Anuradha Mahadevan, Ravi K. Ujjinamatada
Life of this patent
Estimating the term…
Abstract
The disclosure provides for resorcinol-based compounds, pharmaceutical compositions made therefrom, and methods of treatment thereof for various disorders, including neoplastic disorders.
Claims19
A resorcinol-based compound having the structure of Formula I:
- or a pharmaceutically acceptable salt, or prodrug thereof, wherein:
- L1 is selected from,
- R1 is selected from H, —OH, an optionally substituted (C5-C12)cycloalkyl, an optionally substituted (C5-C12)cycloalkenyl, an optionally substituted (C5-C12)cycloalkynyl, an optionally substituted aryl, an optionally substituted heterocycle, and an optionally substituted extended mixed ring system;
- R2, R4, R6, and R7 are each independently selected from H or a (C1-C3)alkyl,
- R3 and R5 are each independently selected from H, hydroxyl, a (C1-C3)alkyl, and a halo;
- R8 is selected from an optionally substituted (C1-C12)alkyl, an optionally substituted (C1-C11) hetero-alkyl, an optionally substituted (C1-C12)alkenyl, an optionally substituted (C1-C11) hetero-alkenyl, an optionally substituted (C1-C12)alkynyl, an optionally substituted (C1-C1) hetero-alkynyl, an optionally substituted aryl, an optionally substituted (C3-C12)cycloalkyl, an optionally substituted (C3-C12)cycloalkenyl, and an optionally substituted heterocycle;
- and
- R9 is selected from H, and a (C1-C3)alkyl.
5 more elements
Dependencies are inferred from the claim text.