US 2024/0033714 A1 · STATIONARY PHASE MATERIALS AND DEVICES USED IN SIZE EXCLUSION CHROMATOGRAPHY

Abstract

Disclosed are methods of making a porous particle material for use as stationary media and related chromatographic separation devices utilizing the disclosed stationary media. The porous particle material has a reduced pore volume which yields improved stability and column lifetime, and additionally has a surface coating, resulting in a surface modified porous particle material that minimizes unwanted adsorption interactions with samples to be tested

Claims20

Dependent claims

A method of making a porous particle material for use as stationary media in chromatographic separation, the method comprising the steps of:

a. reducing the pore volume of the particle material from an initial pore volume to a final pore volume;
b. hydrating the porous particle material;
and
c. coating the porous particle material with a hydrophilic compound to obtain a surface modified porous particle material.

1 more element

Dependencies are inferred from the claim text.

Facts

Application

18/360,609Filed 27 Jul 2023

Priority

28 Jul 2022

Published

1 Feb 2024

Term ends

Not estimatedThe source records don’t support an estimate.

Classification16 codes

B01J 20/3263
The functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur…:…
B01D 15/34
Characterised by the separation mechanism: size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
B01J 20/103
Comprising silica or silicate: comprising silica
B01J 20/28004
Characterised by their physical properties: sorbent size or size distribution, e.g. particle size

Stationary phase materials and devices used in size exclusion chromatography

Life of this patent

Stationary phase materials and devices used in size exclusion chromatography

Life of this patent

Abstract

Claims20