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OwnerDavid BAKER, Jue WANG +10inventors
InventorsDavid BAKER, Jue WANG, Robert RAGOTTE, Lukas MILLES, Joseph L. WATSON, David JUERGENS, Sidney LISANZA, Amijai SARAGOVI, Wei YANG, Derrick HICKS, Douglas TISCHER, Thomas SCHLICHTHAERLE
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De novo designed proteins with binding activity are disclosed, which were designed starting from a desired functional site and jointly filling in the missing sequence and structure needed to complete the protein, and uses of the binding proteins.
A polypeptide comprising an amino acid sequence at least 75%, 80%, 85%, 90%, 91%, 92%, 93% 94%, 95%, 96%, 97% 98%, 99% or 100% identical to the amino acid sequence selected from SEQ TD NO:1-15, wherein any N-terminal methionine residues are optional and may be present or absent.
Dependencies are inferred from the claim text.