Therapies for cancer using small molecules that bind to and inhibit rail interacting proteins

A method of treating or preventing cancer in a subject, the method comprising:

• administering to the subject a composition,
• wherein the composition comprises at least one compound selected from the group consisting of:
• derivatives thereof, or combinations thereof;
• wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, and R15 are each independently selected from the group consisting of an alkane, an alkene, an alkyne, a benzene derivative, an alkyl, an alkenyl, an alkynyl, a phenol, a phenyl, a haloalkane, a fluoroalkane, a chloroalkane, a bromoalkane, an iodoalkane, an alcohol, a ketone, an aldehyde, an acyl halide, a carbonate, a carboxylic acid, an ester, a methoxy, a hydroperoxide, a peroxide, an ether, a hemiacetal, a hemiketal, an acetal, a ketal, an orthoester, a heterocycle, an orthocarbonate ester, an organic acid anhydride, a hydroxyl, a carbonyl, an aldehyde, a haloformyl, a carbonate ester, a anhydride, an amide, an amine, an imine, an imide, an azide, an azo, a cyanate, a nitrate, a nitrile, a nitrite, a nitro, a nitroso, an oxime, a pyridine, a pyridine derivative, a carbamate ester, a carbamate, a thiol, a sulfide, a disulfide, a sulfoxide, a sulfone, a sulfinic acid, a sulfonic acid, a sulfonate ester, a thiocyanate, a thioketone, a thial, a thiocarboxylic acid, a thioester, a dithiocarboxylic acid, a dithiocarboxylic acid ester, a phosphine, a phosphonic acid, a phosphate, a phosphodiester, H, C, F, CH3, AcHN, CONH2, CF3, MeHN,
• derivatives thereof, or combinations thereof;
• wherein Z1, Z2, and Z3 are each independently selected from the group consisting of O, NH, CH2, S, Se, or combinations thereof;
• and
• wherein X selected from the group consisting of H, a halogen, fluorine, chlorine, bromine, iodine, or combinations thereof.