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US 2023/0414556 A1Published application
Nano-hepatic targeted epigallocatechin gallate in dyslipidemia
OwnerShaker A. Mousainventor
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Abstract
A nanoparticle structure and a method for lowering lipids in a mammal by administering the nanoparticle structure to the mammal. The nanoparticle structure includes a hepatic targeted nanoparticle and one or more substances encapsulated within the hepatic targeted nanoparticle. The nanoparticle includes chitosan and glycyrrhetinic acid (GA) covalently linked by an amide bond which occurs between an amino group of chitosan and a carboxylic acid group of GA. The one or more substances comprise (−)-Epigallocatechin-3-gallate (EGCG).
Claims14
A nanoparticle structure, comprising:
- a positively surface charged hepatic targeted nanoparticle;
- and
- one or more substances nano-encapsulated within the hepatic targeted nanoparticle,
- wherein the targeted nanoparticle comprises chitosan and glycyrrhetinic acid (GA) covalently linked by an amide bond which occurs between an amino group of chitosan and a carboxylic acid group of GA, and
- wherein the one or more substances comprise (−)-Epigallocatechin-3-gallate (EGCG).
2 more elements
Dependencies are inferred from the claim text.