Methods for optimization of placement of spinal cord epidural stimulation unit
AssigneeUniversity of Louisville Research Foundation, Inc.
InventorsSusan J. Harkema, Samineh Mesbah, Maxwell Boakye, Claudia Angeli, Yangsheng Chen
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Abstract
Methods for optimization of surgical placement of an implantable electrode for spinal cord epidural stimulation of a subject include creating a computational model of the subject spinal cord based on medical imagery, determining the position of the lumbosacral enlargement, and determining an optimal placement to maximize volumetric coverage of the lumbosacral enlargement by the implantable electrode.
Claims19
1) A method of optimizing electrode placement for spinal cord epidural stimulation, the method comprising:
- receiving at least one medical image of a spinal cord and surrounding vertebral column;
- constructing, using a computer, a three-dimensional model of at least a portion of the spinal cord, the three-dimensional model based at least in part on the at least one medical image;
- determining the position of a lumbosacral enlargement of the spinal cord in the three-dimensional model based at least in part on the at least one medical image;
- and
- determining an optimal placement of an implantable electrode, wherein the optimal placement maximizes coverage of the lumbosacral enlargement by the implantable electrode.
11) A method of optimizing electrode placement for spinal cord epidural stimulation, the method comprising:
- receiving at least one medical image of a spinal cord and surrounding vertebral column;
- identifying, based on the at least one medical image, at least one nerve root exiting the vertebral column and back-tracing the at least one nerve root to determine a position of at least one spinal cord segment;
- constructing a three-dimensional model of at least a portion of the spinal cord, the three-dimensional model based at least in part on the at least one medical image;
- determining the position of a lumbosacral enlargement of the spinal cord in the three-dimensional model based at least in part on the position of the at least one spinal cord segment;
- and
- determining an optimal placement of an implantable electrode, wherein the optimal placement maximizes coverage of the lumbosacral enlargement by the implantable electrode.
Dependencies are inferred from the claim text.