Methods and materials for assessing radiation exposure
OwnerAlexandra Crook, Aline De Lima Leite +3inventors
InventorsAlexandra Crook, Aline De Lima Leite, Thomas Payne, Fatema Bhinderwala, Robert Powers
Life of this patent
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Abstract
This document relates to methods and materials for assessing radiation exposure. For example, methods and materials that can be used to determine whether a mammal (e.g., a human) has been exposed to radiation and/or whether a mammal (e.g., a human) is at risk of developing one or more radiation injuries (e.g., cutaneous radiation injury (CRI) and/or acute radiation syndrome (ARS)) following radiation exposure (e.g., radiation therapy) are provided.
Claims26
1-13. (canceled)
A method for treating a mammal having cancer, wherein said method comprises:
- (a) detecting an absence of an altered level of at least five metabolites in a sample from said mammal;
- and
- (b) administering a radiation therapy to said mammal.
A method for treating a mammal having cancer, wherein said method comprises:
- (a) detecting an absence of at least one enriched metabolic pathway in a sample from said mammal;
- and
- (b) administering a radiation therapy to said mammal.
A method for treating a mammal having cancer, wherein said method comprises:
- (a) detecting a presence of an altered level of at least five metabolites in a sample from said mammal;
- and
- (b) administering a cancer treatment to said mammal, wherein said cancer treatment is not a radiation therapy.
A method for treating a mammal having cancer, wherein said method comprises:
- (a) detecting a presence of at least one enriched metabolic pathway in a sample from said mammal;
- and
- (b) administering a cancer treatment to said mammal, wherein said cancer treatment is not a radiation therapy.
32-45. (canceled)
Dependencies are inferred from the claim text.