Microorganisms capable of producing poly(hiba) from feedstock
AssigneeIndustrial Microbes, Inc.
InventorsElizabeth Jane CLARKE, Derek Lorin GREENFIELD, Noah Charles HELMAN, Timothy Brian ROTH, Nyaradzo DZVOVA
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Abstract
The present disclosure relates to microorganisms capable of producing poly(hydroxyisobutyric acid) (poly(HIBA)) from feedstocks and methods of producing poly(HIBA), methacrylic acid (MAA), and methacrylate esters (MAE) from feedstocks.
Claims24
An engineered microorganism, comprising a CoA-ligase and a PHA polymerase, capable of producing a poly(HIBA) from a feedstock.
The engineered microorganism of any of the preceding claims, wherein the engineered microorganism further comprises an engineered pathway for producing a hydroxyisobutyric acid (HIBA) from the feedstock.
A method of producing a poly(hydroxyisobutyric acid) (poly(HIBA)) from a feedstock, the method comprising:
- 1) providing a nutrient medium comprising the feedstock;
- and
- 2) culturing an engineered microorganism in the nutrient medium, the engineered microorganism comprising a CoA-ligase and a polyhydroxyalkanoate (PHA) polymerase.
Dependencies are inferred from the claim text.