Light inhibitors for scleroderma and skin fibrotic disease treatment
AssigneeLa Jolla Institute for Allergy and Immunology
InventorsMichael CROFT, Rana HERRO
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Abstract
Methods of treating inflammatory conditions, disease and disorders of skin are provided. Methods include, for example, contacting or administering a sufficient amount of a LIGHT inhibitor to a subject to treat skin inflammation, skin fibrosis, or a skin fibrotic disease or disorder such as scleroderma, atopic dermatitis, nephrogenic fibrosing dermopathy, mixed connective tissue disease, scleromyxedema, scleredema, keloid, sclerodactyly, or eosinophilic fasciitis.
Claims18
-43. (canceled)
A method of treating atopic dermatitis, comprising administering a sufficient amount of an inhibitor of LIGHT (p30 polypeptide) to a subject in need thereof to reduce or inhibit the atopic dermatitis in the subject.
Dependencies are inferred from the claim text.