Uv therapy protocol for treatment of non-dermatological chronic conditions
AssigneeLumaVive LLC
InventorsKenneth N. Oif, Michael G. Kaufman
Life of this patent
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Abstract
Methods for a generally safe and effective therapy to lower excessive and chronic inflammation via the promotion of the body's powerful anti-inflammatory Interleukin-10 cytokine and re-activation of dormant T regulatory cells are provided. The methods balance the safety and efficacy of both Interleukin-10 (IL-10) and Treg optimization with excessive risk of UV overexposure to treat and improve several chronic non-dermatological conditions.
Claims30
A method of treating a non-dermatological autoimmune condition or other chronic non-dermatological condition in a subject with a pause and reset phototherapy protocol, comprising:
- administering ultraviolet B (UVB) therapy for a first set of phototherapy treatments having escalating dosage levels over time, wherein the first set of phototherapy treatments are defined by a pause and reset phototherapy protocol;
- pausing treatment for a pause period, wherein the pause period has a length of time that is based on the pause and reset phototherapy protocol, and wherein the length of time is at least about two weeks;
- and
- administering UVB therapy for a second set of phototherapy treatments having escalating dosage levels over time, wherein the second set of phototherapy treatments are defined by a pause and reset phototherapy protocol.
A method of treating a chronic non-dermatological condition in a subject, comprising:
- administering ultraviolet B (UVB) therapy for a first set of phototherapy treatments, the first set of phototherapy treatments having a first initial dosage level and a first final dosage level, wherein the first initial dosage level is less than the first final dosage level;
- and
- in conjunction with the administration of the first set of phototherapy treatments, administering a disease-modifying therapy (DMT) to the subject for treatment of the chronic non-dermatological condition.
A method of treating Multiple Sclerosis in a subject with a pause and reset phototherapy protocol, comprising:
- administering ultraviolet B (UVB) therapy for a first set of phototherapy treatments having escalating dosage levels over time, wherein the first set of phototherapy treatments are defined by a pause and reset phototherapy protocol;
- pausing treatment for a pause period, wherein the pause period has a length of time that is based on the pause and reset phototherapy protocol, and wherein the length of time is at least about two weeks;
- and
- administering UVB therapy for a second set of phototherapy treatments having escalating dosage levels over time, wherein the second set of phototherapy treatments are defined by a pause and reset phototherapy protocol.
Dependencies are inferred from the claim text.