Composite Materials for Uses in Cardiac and Other Tissue Repair

Abstract

This disclosure relates to composite materials for repairing a tissue of a subject by implanting the composite material in or on the tissue, e.g., heart tissue. In certain embodiments, the composite material comprises a first material and a second material coated on the first material, wherein the first material is an inert substantially non-biodegradable material providing mechanical support; wherein the second material is a biodegradable active material attracting cells from the body of a subject, and wherein, when the composite material is implanted, cells integrate into the inert material providing a remodeled tissue. In certain embodiments, this disclosure relates to methods of using the composite material wherein the inert and active materials allow for remodeling of the material in vivo.

Dependencies are inferred from the claim text.