Methods and compositions related to receptor-mediated glucose sensing

Abstract

Disclosed herein is a method of modulating cell metabolism in skeletal muscle in a subject in need thereof, the method comprising: identifying a subject in need of modulation of cell metabolism in skeletal muscle; and administering to the subject a modulator of skeletal muscle in T1R2. Also disclosed herein is a method of identifying a modulator of T1R2 in skeletal muscle, the method comprising providing muscle-related cells, exposing the cells to a potential modulator of T1R2, and determining modulation, thereby identifying a modulator of T1R2. Further disclosed are compositions identified by this method.

Dependencies are inferred from the claim text.