Systems and methods for treating ocular disease with an intraocular lens and refractive index writing

A method of treating an ocular disease of a subject having an implanted intraocular lens (IOL), the method comprising:

• determining visual needs of a subject that are associated with an ocular disease of the subject;
• determining a pattern of a plurality of pulses of radiation to apply, by refractive index writing, to one or more selected areas of the IOL, wherein the plurality of pulses are configured to induce a change in the implanted IOL to adapt the optical performance of the IOL to the visual needs of the subject;
• and
• applying, according to the determined pattern, the plurality of pulses of radiation to the one or more selected areas of the IOL.