System and method for remote neurobehavioral testing
AssigneeThe Trustees of Princeton University
InventorsHenk-Jan BOELE, Samuel S.-H. WANG
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Abstract
A system and method for neurobehavioral testing, including eyeblink conditioning and prepulse inhibition, without air puffs, that utilizes an electronic device with a light source, a camera, and a speaker, and makes assessments based on the degree to which an eyelid is closed after a user is exposed to conditional and unconditional stimuli.
Claims22
A method for eyeblink conditioning without air puffs, comprising:
- a. starting to emit a sound from a speaker on a mobile device;
- b. capturing one or more initial images of at least one eye while the sound is being emitted;
- c. emitting a light from a light source on the mobile device while the sound is being emitted, the emitting of light beginning a fixed period of time after the sound began emitting;
- d. capturing one or more final images of the at least one eye while the light and sound are being emitted;
- e. stopping the emitting of the sound and the light;
- and
- f. repeating steps a-e,
- wherein no equipment is attached to a user's face.
A method for prepulse inhibition in a user, comprising:
- emitting a white noise prepulse, the white noise prepulse having a first strength configured to not elicit a startle reflex in the user;
- and
- after a delay in which no white noise is emitted, emitting a white noise pulse having a second strength configured to elicit a startle reflex in the user, the second strength being greater than the first strength.
A device for eyeblink conditioning without air puffs, comprising one or more processors configured with instructions that, when executed, cause the one or more processors to:
- a. cause a speaker configured to start emitting a sound at a first point in time and stop emitting a sound at a second point in time;
- b. cause a light source configured to start emitting light at a third point in time and stop emitting light at the second point in time, where the third point in time follows the first point in time after a fixed delay interval;
- c. receive one or more first images of at least one eye from a camera while the speaker is emitting a sound and the light source is not emitting light;
- d. receive one or more second images of the at least one eye from the camera while the speaker is emitting a sound and the light source is emitting light;
- and
- e. determine a degree of openness of the at least one eye in each of the one or more first images and the one or more second images.
Dependencies are inferred from the claim text.