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US 2023/0404066 A1Published application
Tissue perfusion and viability sensing system
AssigneeVascular Perfusion Solutions, Inc.
InventorsIsrael Jessop, Exal Cisneros, Leonid Bunegin
Life of this patent
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Abstract
A perfusion system includes a perfusate source and a perfusion distributor coupled to the perfusate source and configured to convey oxygen containing perfusate from the perfusate source to tissue and exhaust carbon dioxide generated by the tissue. A carbon dioxide sensor is coupled to sense the carbon dioxide generated by the tissue, which can then be used to provide a measure of tissue viability.
Claims20
A perfusion system comprising:
- a perfusate source;
- a perfusate distributor coupled to the perfusate source and configured to convey oxygen containing perfusate from the perfusate source to tissue and exhaust carbon dioxide generated by the tissue;
- and
- a carbon dioxide sensor coupled to sense the carbon dioxide generated by the tissue.
1 more element
A perfusion system comprising:
- a gas exchanger to receive oxygen from an oxygen source;
- a perfusate circulation system coupled to the gas exchanger and configured to convey oxygen containing perfusate from the gas exchanger to tissue and return carbon dioxide containing perfusate from the tissue to the gas exchanger;
- an exhaust conduit coupled to the gas exchanger to receive gas containing carbon dioxide removed from the returned carbon dioxide containing perfusate;
- a carbon dioxide sensor coupled to the exhaust conduit to measure carbon dioxide concentration in the carbon dioxide-containing gas;
- and
- a controller coupled to receive carbon dioxide indication from the carbon dioxide sensor to determine a rate of carbon dioxide generation by the tissue based on the carbon dioxide data, and a flow rate of the gas.
3 more elements
A method comprising:
- perfusing tissue with an oxygenated perfusate;
- receiving perfusate from the tissue;
- measuring carbon dioxide generated by the tissue;
- and
- computing a measure of tissue viability based on the measured carbon dioxide, flow rate of the perfusate, and physical characteristics of the tissue.
2 more elements
Dependencies are inferred from the claim text.