Systems and methods for integration of microbial sequencing with growth recipes
AssigneeBattelle Memorial Institute
InventorDavid C. Glasbrenner
Life of this patent
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Abstract
The invention relates to microbial growth. The invention provides a system and method for rapidly and reliably generating information for microbial growth for known and unknown microorganisms. Using sequence information of the microorganisms in a sample, the system and method identifies the microorganisms contained in the sample and generates growth recipes and conditions for each. The recipes are identified from a recipe database or alternatively created by taking into consideration the species, unique characteristics and growth requirements of the user-desired microbe.
Claims14
A method for microbial growth, comprising:
- a. receiving and analyzing of sequencing data from one or more microbes supplied in a biological sample, wherein sequencing data may include 16s metagenomic sequencing data, transcriptome data, amplicon sequencing data, full genome sequencing data, proteomic sequencing data, metabolomics data and pathway analysis;
- b. identifying of microbial species in the sample;
- c. accessing a repository of growth recipes and recommending at least one growth recipe for each microbe on the list of microbes;
- d. in the event that the microbial recipe for a species-type does not exist, generating a recipe that matches a close genetic relative;
- and
- e. generating a recipe for a particular microbe by integrating information from a combination of input sequencing data as stated in step (a).
Dependencies are inferred from the claim text.