Exosomes containing mirnas targeting her2 synthesis and pharmaceutical compositions
AssigneeImmvira Co., Limited
InventorsXiaoqing CHEN, Lei WANG, Xusha ZHOU, Grace Guoying ZHOU
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Abstract
Disclosed is an engineered exosome comprising a miRNA targeting human epidermal growth factor receptor 2 (HER2) synthesis and a ligand displayed on a membrane of the exosome for specific binding to a HER2 protein expressed on a cancer cell.
Claims28
An engineered exosome comprising a miRNA targeting human epidermal growth factor receptor 2 (HER2) synthesis and a ligand displayed on a membrane of the exosome for specific binding to a HER2 protein expressed on a cancer cell.
An engineered exosome comprising a miRNA targeting human epidermal growth factor receptor 2 (HER2) synthesis, wherein the miRNA has a seed sequence having a nucleotide sequence as shown in SEQ ID NO. 1, 2 or an equivalent thereof.
Dependencies are inferred from the claim text.