Ocular-tension-increasing agent capable of being deprived of drug activity by temperature control
AssigneeUniversity of Yamanashi
InventorsYuji TANAKA, Kenji KASHIWAGI, Shigehito OSAWA
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Abstract
The disclosure provides an ocular tension increasing agent containing a temperature responsive polymer. Ocular tension can be increased by administering an ocular tension increasing agent according to the present invention to a predetermined region of an eye and ocular tension can be controlled, if necessary, by temperature.
Claims27
A method for modulating ocular tension in a subject, comprising administering a temperature responsive polymer to an anterior chamber of an eyeball in the subject to increase the ocular tension of the subject, and cooling the eyeball that has received the temperature responsive polymer to decrease the ocular tension.
(canceled)
A composition comprising polyoxazoline (POx) and a block copolymer (POxPEG) comprising a polyethylene glycol block and a polyoxazoline block.
13-14. (canceled)
Dependencies are inferred from the claim text.