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US 2023/0398064 A1Published application
Compositions and methods for the treatment of presbyopia
AssigneeLenz Therapeutics, Inc.
InventorsGerald HORN, Lee NORDAN
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Abstract
The invention provides compositions and methods for the treatment of presbyopia. The compositions comprise aceclidine hydrochloride, polysorbate 80, mannitol, anhydrous hypromellose, disodium edetate dihydrate, benzalkonium chloride, sorbic acid and anhydrous sodium citrate and optionally tropicamide.
Claims23
A cold chain storage system comprising (i) an opthalmological composition comprising aceclidine in a stable solution, wherein the aceclidine remains in solution when the solution is maintained at about 2° C. to about 8° C.;
- and (ii) a container suitable for cold chain storage.
A method of treating presbyopia in a subject in need thereof, the method comprising:
- a. providing an opthalmological composition comprising aceclidine in a stable solution, wherein the aceclidine remains in solution when the solution is maintained at about 2° C. to about 8° C.;
- b. storing the opthalmological composition at a temperature from about 2° C. to about 8° C.;
- and
- c. administering the opthalmological composition to an eye of the subject.
1 more element
Dependencies are inferred from the claim text.