Systems and methods for assessing cerebrovascular reactivity

Abstract

The disclosed subject matter provides a device and a method for inducing and sustaining hypercapnia of a subject. The device can include a tube, a face mask for breathing of the subject, a gas collection reservoir for collecting an expired gas from the subject, a valve chamber, a sensor for detecting a carbon dioxide level from the expired gas from the subject, and a controller configured to control a partition of the valve chamber for changing a gas composition in the valve chamber based on the readings of the sensor. The valve chamber can include a first opening, a second opening, and a third opening, wherein the first opening can be configured to allow an external air flowing into the valve chamber, and the expired gas flowing out from the valve chamber, wherein the second opening, coupled to the face mask through the tube, can be configured to allow a gas passage between the subject and the valve chamber, wherein the third opening, coupled to the gas collection reservoir though the tube, can be configured to allow a gas passage between the valve chamber and the gas collection reservoir.

Dependencies are inferred from the claim text.