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US 2023/0390307 A1Published application
Peg-free aqueous suspensions for parenteral administration of a corticosteroid
AssigneePfizer Inc.
InventorsOmar Abdelrahman Salman, Joel Aaron Bergman
Life of this patent
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Abstract
A parenteral aqueous suspension formulation for corticosteroids without polyethylene glycol (PEG) or Polysorbate (PS) that has better resuspendability, longer stability compared to commercially available formulations, and additionally allows for stable formulations of higher concentrations of corticosteroids that were not previously feasible. Preferably, the corticosteroid is methylprednisolone acetate or medroxyprogesterone acetate.
Claims24
A pharmaceutical aqueous suspension formulation for parental use comprising a corticosteroid, a quaternary ammonium compound, a tonicity agent, and water;
- and wherein the formulation is essentially free of each of polyethylene glycol and polysorbate.
Dependencies are inferred from the claim text.