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US 2023/0390302 A1Published application
Pharmaceutical formulation
AssigneeHoffmann-La Roche Inc.
InventorsPatrick BUSSON, Georg HUMMEL, Thomas Peter Wilhelm KNOBLOCH
Life of this patent
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Abstract
The present invention relates to a pharmaceutical composition of 8-chloro-5-methyl-1-[4-(2-pyridyloxy)cyclohexyl]-4,6-dihydro-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine, a process for the preparation thereof and its use in the treatment of diseases.
Claims6
A pharmaceutical composition comprising a kernel,
- the kernel consisting of:
- i. 5% by weight of a compound of compound of formula I
- ii. a disintegrant;
- iii. a filler;
- iv. a glidant and
- v. a lubricant;
- wherein,
- i) the disintegrant is 5% by weight croscarmellose sodium,
- ii) the filler is 70% by weight mannitol and 15% by weight starch,
- iii) the glidant is 2% by weight colloidal anhydrous silica, and
- iv) the lubricant is 3% by weight sodium stearyl fumarate.
8 more elements
Dependencies are inferred from the claim text.