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US 2023/0390230 A1Published application
Pharmaceutical composition
AssigneeNeuroPro Therapeutics, Inc.
InventorDaryl W. HOCHMAN
Life of this patent
Estimating the term…
Abstract
Described herein is Bumetanide Dibenzylamide, methods for synthesizing Bumetanide Dibenzylamide, pharmaceutical compositions thereof, and methods of dosing Bumetanide Dibenzylamide for treating epilepsy or other indication for which bumetanide is effective.
Claims26
A pharmaceutical composition comprising:
- a Bumetanide derivative as an active ingredient selected from one or more of Bumetanide Dibenzylamide Bumetanide Diethylamide, and Bumetanide Morpholinoamide, and one or more solubilizers.
(canceled)
6-12. (canceled)
16-34. (canceled)
A method for treating a disease or disorder in a patient in need thereof comprising:
- administering a pharmaceutical composition comprising:
- a Bumetanide derivative as an active ingredient selected from one or more of Bumetanide Dibenzylamide Bumetanide Diethylamide, and Bumetanide Morpholinoamide, and one or more solubilizers.
39-46. (canceled)
50-87. (canceled)
A pharmaceutical composition, comprising an amide prodrug derivative of Bumetanide in a self-emulsifying drug delivery system (SEDDS).
92-106. (canceled)
Dependencies are inferred from the claim text.