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US 2023/0390212 A1Published application
Time released biodegradable or bioerodible microspheres or microparticles suspended in a solidifying depot-forming injectable drug formulation
AssigneeAllergan, Inc.
InventorsDavid A. Marsh, Hongwen M. Rivers
Life of this patent
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Abstract
A composite drug delivery material may be injected into an eye of a human being or mammal to provide sustained delivery of the drug. A composite drug delivery material may include a plurality of microparticles dispersed in a media composition. The microparticles may contain a drug and a coating comprising a bioerodible material or a biodegradable material, and the media composition includes the drug dispersed in a depot-forming material. The media composition may gel or solidify upon injection into the eye.
Claims15
A composite drug delivery material comprising:
- a plurality of microparticles dispersed in a media composition;
- wherein the microparticles comprise:
- a drug;
- and
- a coating comprising a bioerodible material or a biodegradable material;
- and
- wherein the media composition comprises the drug dispersed in a depot-forming material;
- and wherein the media composition is in a liquid form before administration and is configured to substantially increase in viscosity during or after being injected into a body of a mammal, so that the form of the media after injection is a solid or a gel.
5 more elements
Dependencies are inferred from the claim text.