Selecting Resins for Use in Chromatography Purification Processes

A system comprising:

• a computing system that includes one or more processors and one or more memories, the one or more memories storing instructions that, when executed by the one or more processors, cause the computing system to, for each of one or more candidate resins
• receive a respective set of resin attribute values, the respective set of resin attribute values including at least one analytical measurement of the candidate resin,
• predict, by applying the respective set of resin attribute values as inputs to a multivariate statistical model, a respective value of a performance indicator for a column chromatography purification process, and
• display the respective value of the performance indicator, or a result based on the respective value of the performance indicator, to a user to facilitate selection of a resin of the one or more candidate resins based at least in part on the one or more predicted respective values of the performance indicator;
• and
• a column chromatography system configured to perform the column chromatography purification process using the selected resin as a stationary phase.

A non-transitory computer-readable medium storing instructions that, when executed by one or more processors or a computing system, cause the computing system to, for each of one or more candidate resins:

• receive a respective set of resin attribute values, the respective set of resin attribute values including at least one analytical measurement of the candidate resin;
• predict, by applying the respective set of resin attribute values as inputs to a multivariate statistical model, a respective value of a performance indicator for a column chromatography purification process;
• and
• display the respective value of the performance indicator, or a result based on the respective value of the performance indicator, to a user to facilitate selection of a resin of the one or more candidate resins, for use as a stationary phase in the column chromatography purification process, based at least in part on the one or more predicted respective values of the performance indicator.