Medicament for treating cancer, immunostimulant, and method for screening for anti-cancer substance

A method for screening for an anti-cancer substance, comprising the steps of:

• (a) bringing cancer cells into contact with a test substance,
• (b) measuring expression level of interferon regulatory factor 7 (IRF7) in the cancer cells of (a), and
• (c) comparing expression level of IRF7 measured in (b) to that in absence of contact with the test substance to identify a substance capable of increasing expression level of IRF7.

A method for screening for an anti-cancer substance, comprising the steps of:

• (a) bringing cancer cells into contact with a test substance,
• (b) measuring expression level of an apolipoprotein in the cancer cells of (a), and
• (c) comparing expression level of the apolipoprotein measured in (b) to that in absence of contact with the test substance to identify a substance capable of increasing expression level of the apolipoprotein.

A method for treating cancer, comprising administering to a mammal in need thereof an effective amount of an apolipoprotein and/or an effective amount of interferon regulatory factor 7.

A method for treating cancer, comprising administering to a mammal in need thereof an effective amount of hemagglutinating virus of Japan-envelope and an effective amount of a T-cell co-stimulator agonist.

A method for stimulating immunity, comprising administering to a mammal in need thereof an effective amount of (i) at least one member selected from the group consisting of an apolipoprotein, interferon regulatory factor 7, and hemagglutinating virus of Japan-envelope and (ii) an effective amount of a T-cell co-stimulator agonist.