Antibiotic therapeutics and uses thereof
OwnerAbraham Jakob DOMBinventor
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Abstract
The invention concerns an antimicrobial formulation comprising at least one antibiotic agent and a polyanhydride carrier.
Claims21
1-48. (canceled)
An antimicrobial formulation comprising at least one antibiotic agent and a carrier in a form of a polyanhydride composed of sebacic acid (SA) and ricinoleic acid (RA), the carrier having a Mw/Mn value between 1 and 2.5.
A method for treating or delaying or preventing progression of an infection or a disease mediated or caused by a bacterium, the method comprising administering an effective amount of an antibiotic agent in a formulation comprising a carrier in a form of a polyanhydride of the formula —(SA-RA)n-, wherein SA is sebacic acid and RA is ricinoleic acid, and wherein n is an integer between 10 and 100, the carrier having a Mw/Mn value between 1 and 2.5 or 1 and 2.
A method for treating or delaying or preventing progression of an infection, the method comprising administering an effective amount of an antibiotic agent in a formulation comprising a carrier prepared by melt condensation of SA and RA.
A kit comprising an antibiotic drug and a carrier in a form of a polyanhydride of the formula —(SA-RA)n-, wherein SA is sebacic acid and RA is ricinoleic acid, and wherein n is an integer between 10 and 100, the carrier having a Mw/Mn value between 1 and 2.5 or 1 and 2;
- and instructions of use.
Dependencies are inferred from the claim text.