Biomolecule analysis method, biomolecule analyzing reagent, and biomolecule analysis device
AssigneeHitachi High-Tech Corporation
InventorRena AKAHORI
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Abstract
A biomolecule analysis method of the present disclosure includes: preparing a biomolecule analysis device including a thin film, a first liquid tank and a second liquid tank separated by the thin film, a first electrode disposed in the first liquid tank, and a second electrode disposed in the second liquid tank; and forming a nanopore in the thin film by applying a first voltage between the first electrode and the second electrode in a state where a nanopore forming solution is enclosed in the first liquid tank and the second liquid tank, wherein the nanopore forming solution contains ammonium ions and sulfate ions.
Claims24
A biomolecule analysis method comprising:
- preparing a biomolecule analysis device including a thin film, a first liquid tank and a second liquid tank separated by the thin film, a first electrode disposed in the first liquid tank, and a second electrode disposed in the second liquid tank;
- and
- forming a nanopore in the thin film by applying a first voltage between the first electrode and the second electrode in a state where a nanopore forming solution is enclosed in the first liquid tank and the second liquid tank,
- wherein the nanopore forming solution contains ammonium ions and sulfate ions.
A biomolecule analysis method comprising:
- preparing a biomolecule analysis device including a thin film having a nanopore, a first liquid tank and a second liquid tank separated by the thin film, a first electrode disposed in the first liquid tank, and a second electrode disposed in the second liquid tank;
- and
- measuring a current flowing between the first electrode and the second electrode by applying a voltage between the first electrode and the second electrode in a state where a measurement solution is enclosed in the first liquid tank and the second liquid tank,
- wherein the measurement solution contains ammonium ions and sulfate ions.
A biomolecule analyzing reagent used for at least one of an application for forming a nanopore in a thin film by dielectric breakdown and an application for analyzing a biomolecule by passing the biomolecule through the nanopore, the biomolecule analyzing reagent comprising ammonium ions and sulfate ions.
A biomolecule analysis device comprising:
- a thin film;
- a first liquid tank and a second liquid tank separated by the thin film and each containing an electrolyte solution;
- a first electrode disposed in the first liquid tank;
- and
- a second electrode disposed in the second liquid tank,
- wherein the electrolyte solution contains ammonium ions and sulfate ions.
Dependencies are inferred from the claim text.