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US 2023/0264186 A1Published application
Devices and methods for tissue sample processing
Assignee10x Genomics, Inc.
InventorsBill Kengli LIN, Siyuan Xing, Hanyoup Kim
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Abstract
Disclosed herein are devices and methods for contacting a tissue sample with liquids to perform a variety of processes and analyses. In various embodiments, the device includes a hydrophilic flow path defined at least in part by a surface pattern (e.g., bounded by hydrophobic regions). The flow path includes a sample area sized to receive a biological sample. The flow path includes at least one valve configured to control flow in the flow path in response to an external stimulus.
Claims22
A device comprising a first surface comprising a first flow path comprising:
- a) a sample area sized for placement of a tissue sample;
- b) a liquid deposition area;
- c) a liquid removal area;
- and
- d) at least one valve disposed to control flow in the flow path in response to an external stimulus;
- wherein the sample area is disposed between the liquid deposition area and the liquid removal area, wherein the flow path is at least partially defined by a surface pattern that is more hydrophobic than the flow path.
3 more elements
Dependencies are inferred from the claim text.