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US 2023/0263156 A1Published application
Systems and methods for ex-vivo organ care
AssigneeTransmedics, Inc.
InventorsWaleed H. HASSANEIN, Richard BRINGHAM, Giovanni CECERE, Tamer I. KHAYAL, Ronald TAYLOR, Hossam ALGAMIL
Life of this patent
Estimating the term…
Abstract
The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions.
Claims31
1-33. (canceled)
A method comprising:
- placing an ex-vivo heart in a chamber of an organ care system;
- connecting the ex-vivo heart to a perfusion fluid circuit of the organ care system;
- starting a pump configured to provide, via the perfusion fluid circuit, a perfusion fluid to the ex-vivo heart;
- synchronizing at least one maximum output of the pump with an r-wave of the ex-vivo heart;
- testing the ex-vivo heart or the organ care system;
- adjusting a setting of the organ care system in response to a result of the testing;
- and
- after adjusting the setting of the organ care system in response to the result of the testing, re-testing the ex-vivo heart or the organ care system.
5 more elements
A method comprising:
- receiving an ex-vivo heart in a chamber of an organ care system,
- the organ care system comprising a perfusion fluid circuit;
- pumping, via a pump coupled to the perfusion fluid circuit, a perfusion fluid to the ex-vivo heart;
- synchronizing at least one maximum output of the pump with an r-wave of the ex-vivo heart;
- allowing for testing of the ex-vivo heart or the organ care system;
- receiving, by the organ care system, an adjustment of a setting of the organ care system in response to a result of the testing of the ex-vivo heart or the organ care system;
- and
- after receiving the adjustment of the setting of the organ care system in response to the result of the testing, allowing for re-testing of the ex-vivo heart or the organ care system.
5 more elements
An organ care system comprising:
- a chamber configured to hold an ex-vivo heart;
- a perfusion fluid circuit comprising a pump,
- wherein the pump is configured to provide, via the perfusion fluid circuit, a perfusion fluid to the ex-vivo heart;
- and
- a controller configured to:
- synchronize at least one maximum output of the pump with an r-wave of the ex-vivo heart;
- and
- receive an adjustment of a setting of the organ care system in response to a result of a testing of the ex-vivo heart or of the organ care system.
5 more elements
Dependencies are inferred from the claim text.