Modulation of endogenous mogroside pathway genes in watermelon and other cucurbits
AssigneeElo Life Systems
InventorsTengfang Huang, Jing Zhou, Hye-ran Lee, Jack Q. Wilkinson, Fayaz Khazi
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Abstract
Provided herein are methods for increasing the level of mogrosides in plants, such as in Cucurbitaceae family plants (e.g., in watermelon), by genetically-modifying such plants to modulate the expression of endogenous mogroside pathway genes. Also disclosed herein are plants with increased levels of mogrosides, extract (e.g., sweetener) from such plants, parts (e.g., juice, seed, pulp, etc.) from such plants, and methods of producing such plants.
Claims44
A method for increasing the production of one or more mogrosides by a cell, the method comprising genetically-modifying the genome of the cell to modulate the expression of one or more endogenous mogroside synthesis pathway genes.
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A method for producing a plant comprising increased levels of one or more mogrosides, the method comprising genetically-modifying the genome of a plant cell or plant part to modulate the expression of one or more endogenous mogroside synthesis pathway genes, and growing a plant from said plant cell or plant part, wherein said plant comprises increased levels of one or more mogrosides compared to a control plant.
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A plant or plant part comprising increased levels of at least one mogroside compared to a control plant, wherein the genome of the plant comprises a genetic modification to modulate the expression of one or more endogenous mogroside synthesis pathway genes.
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Dependencies are inferred from the claim text.